• Assessment of LDL and HDL Subfractions and Metrics of HDL Function in High-Risk Patients of Cardiovascular Disease: Evaluation of Four Different Interventions 

      Kjellmo, Christian Abendstein (Doctoral thesis; Doktorgradsavhandling, 2023-10-27)
      Our research focused on assessing lipoprotein subfractions using the Lipoprint LDL® and HDL® system and evaluating metrics associated with HDL function. We examined data from four intervention trials involving high-risk patients of atherosclerotic cardiovascular disease (ASCVD). The interventions included lifestyle changes followed by bariatric surgery for morbidly obese patients, statin and ezetimibe ...
    • Effect of N-3 Polyunsaturated Fatty Acids on Lipid Composition in Familial Hypercholesterolemia: A Randomized Crossover Trial 

      Hande, Liv Nesse; Kjellmo, Christian Abendstein; Pettersen, Kristin; Ljunggren, Stefan; Karlsson, Helen; Cederbrant, Karin; Marcusson-Ståhl, Maritha; Hovland, Anders Wilhelm; Lappegård, Knut Tore (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-06-27)
      Individuals with familial hypercholesterolemia (FH) have an increased risk of cardiovascular disease. Treatment is mainly low-density lipoprotein cholesterol (LDL-C) reduction. How omega-3 polyunsaturated fatty acids (n-3 PUFAs) supplements affect lipoproteins in FH subjects is unknown. We hypothesized that a high-dose n-3 PUFA supplement would reduce atherogenic lipoproteins and influence the ...
    • High-density lipoprotein subfractions: Much ado about nothing or clinically important? 

      Lappegård, Knut Tore; Kjellmo, Christian Abendstein; Hovland, Anders (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-07-18)
      High-density lipoproteins (HDL) are a heterogenous group of plasma molecules with a large variety in composition. There is a wide specter in lipid content and the number of different proteins that has been associated with HDL is approaching 100. Given this heterogeneity and the fact that the total amount of HDL is inversely related to the risk of coronary heart disease (CHD), there has been ...